Toxoplasma pneumonitis: fatal presentation of disseminated toxoplasmosis in a patient with AIDS.

نویسندگان

  • C Bergin
  • M Murphy
  • D Lyons
  • E Gaffney
  • F M Mulcahy
چکیده

Toxoplasma gondii infection is an uncommon cause of pneumonitis in patients with acquired immune deficiency syndrome (AIDS). We report a case of fatal pulmonary toxoplasmosis, which clinically resembled Pneumocystis carinii pneumonia (PCP). Conventional diagnostic methods for toxoplasmosis lack sensitivity. Bronchoscopy and histological evaluation of transbronchial biopsy specimens failed to identify the infecting organism. At autopsy there was evidence of disseminated infection.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Asymptomatic diffuse "encephalitic" cerebral toxoplasmosis in a patient with chronic lymphocytic leukemia: case report and review of the literature.

Opportunistic infections account for the majority of central nervous system lesions in adult immunosuppressed patients. In this setting, toxoplasmosis typically manifests as multiple abscesses readily seen on routine neuroimaging studies. Asymptomatic, widely disseminated Toxoplasma cysts without parenchymal reaction are also recognized. In contrast, widespread parasites in the brain parenchyma...

متن کامل

Disseminated toxoplasmosis in an HIV positive patient in cART era

Toxoplasmosis is a disease caused by the intracellular parasite Toxoplasma gondii. Toxoplasmosis is considered one of the most common cerebral opportunistic infections in HIV-AIDS patients. It develops when CD4 count falls below 100 cells/cmm, either from acute exposure to the parasite or from reactivation of latent infection. These patients may also develop extra-cerebral toxoplasmosis such as...

متن کامل

Failure to diagnose fatal disseminated toxoplasmosis in a bone marrow transplant recipient: the possible significance of declining antibody titres.

A 46-year-old patient with acute myelogenous leukaemia developed lethal disseminated toxoplasmosis 8 weeks after allogeneic bone marrow transplantation. Clinical features included pulmonary infiltrates, respiratory insufficiency and neurological signs. Post-transplantation toxoplasma serological tests were characterised by declining IgG titres and failure to detect IgM, whereas titres of IgG ag...

متن کامل

CASE REPORT Failure to diagnose fatal disseminated toxoplasmosis in a bone marrow transplant recipient: the possible significance of declining antibody titres

Please be advised that this information was generated on 2017-03-31 and may be subject to change. S u m m ary A 46-year-old patient with acute myelogenous leukaemia developed lethal dis­ seminated toxoplasmosis 8 weeks after allogeneic bone marrow transplantation. Clinical features included pulmonary infiltrates, respiratory insufficiency and neurological signs. Post-transplantation toxoplasma ...

متن کامل

A Case Report of Cerebral Toxoplasmosis in An HIV-Positive Patient: Risk of Possible Transmission through Contaminated Water/Food

Introduction: Toxoplasma gondii is an obligatory intracellular protozoan with a worldwide distribution. We reported here the cerebral toxoplasmosis in an Iranian HIV-positive patient. Case report: A 35-year-old woman that hospitalized at Golestan province, in summer 2016 because of dizziness, fever, and headache. After treatment, she showed severe pain and then paralysis symptoms. Magnetic res...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The European respiratory journal

دوره 5 8  شماره 

صفحات  -

تاریخ انتشار 1992